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Sravanti Uppaluri

Email: [email protected]

Sravanti is broadly interested in understanding mechanisms of growth and size control in biology. She studies this problem across a wide range of length scales, from the cellular to organismal and population levels. She is particularly interested in using an interdisciplinary approach (drawing from physics, biology and chemistry) to tackle these questions experimentally.

In conjunction with her research, she is deeply interested in participating in teaching and mentoring activities as well engaging with the community in order to generate of scientific temperament in the public.

Academic Qualifications
  • PhD. - Max Planck Institute for Dynamics and Self-Organization, Goettingen, Germany
  • MASc. - University of Toronto, Toronto, Canada
  • BSc.- McMaster University, Hamilton, Canada
Areas of Interest

Biophysics, Developmental biology, Systems biology, Soft matter

Click here to listen to Sravanti talking about areas of interest and current research work.

Subjects Taught at the University
  • Molecular Biology
  • Biochemistry
  • Biophysics
  • Cell and developmental biology
Publications and Writings
  • Uppaluri S, Brangwynne CP. A size threshold governs Caenorhabditis elegans developmental progression. Proceedings of the Royal Society B. 282: 20151283, 2015.
  • Gilpin W, Uppaluri S, Brangwynne CP. Worms under pressure: bulk mechanical properties of C. elegans are independent of the cuticle. Biophysical Journal. 108(8):1887-98. Apr 21, 2015 **Work with Undergraduate Mentee
  • Hochstetter A, Stellamanns E, Deshpande S, Uppaluri S, Engstler M, Pfohl T, Microuidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes. Lab Chip (15):1961-1968, 2015
  • Stellamanns E, Uppaluri S, Hochstetter A, Heddergott N, Engstler M, Pfohl T. Optical trapping reveals propulsion forces, power generation and motility efficiency of the unicellular parasites Trypanosoma brucei brucei". Scientic Reports 4(6515), Oct 1, 2014.
  • Heddergott N, Krueger N, Wei A, Stellamanns E, Uppaluri S, Pfohl T, Engstler M. Trypanosome Motion Represents an Adaptation to the Crowded Environment of the Vertebrate Bloodstream. PLoS Pathogens 8(11): e1003023, 2012.
  • Uppaluri S, Heddergott N, Stellamanns E, Herminghaus S, Engstler M, Pfohl T. Flow loading induces oscillatory trajectories in bloodstream parasites. Biophysical Journal. 103(6):1162-9 Sep 19, 2012.
  • Uppaluri S, Nagler J, Stellamanns E, Heddergott N, Herminghaus S, Engstler M, Pfohl T. Impact of microscopic motility on the swimming behaviour of parasites: stiffer trypanosomes are more directional. PLoS Computational Biology, 7(6): e1002058, 2011. Featured article
  • Zaburdaev V, Uppaluri S, Friedrich R, Engstler M, Pfohl T, Stark H, Langevin dynamics deciphers the motility pattern of swimming parasites". Physical Review Letters, 20(106):208103, May 2011.

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