Faculty research at Azim Premji University spans across the social sciences, natural and physical sciences, development, and education. A defining feature of research at the University is its interdisciplinary character. Faculty draw on diverse perspectives and methodologies to address complex questions that cut across conventional disciplinary boundaries. 

Researchers engage with questions that are central to understanding contemporary society, including education, livelihoods, development, governance, public policy, inequality and social justice. They examine issues such as caste, gender, political economy, sustainability, and climate change, while also exploring areas related to culture, media, literature, and history.

Faculty also investigate questions across the life sciences, physical sciences, mathematics, information sciences, and psychology. Their work spans topics such as biological invasions, forest resilience, quantum chromodynamics, computational chemistry, geometric group theory, data science, topology and neurological and mental health disorders.