Neetu Kalra

Neetu Kalra has completed her post-doctoral training at the National Cancer Institute (NCI), National Institute of Health (NIH), Bethesda, USA. Her research primarily focused on conducting preclinical investigations of drugs aimed at understanding the mechanisms involved in improving the prognosis of rare types of cancer.

During her time at the Indian Institute of Science Education and Research (IISER), Bhopal as a visiting faculty, she made significant contributions to both academic teachings and research endeavours.

Notably, she actively participated in a team dedicated to developing antibody-drug conjugates targeting Breast Cancer, resulting in numerous publications in prestigious international journals. Before her current position, she worked at the Vellore Institute of Technology (VIT), Bhopal as an Assistant Professor.

Publications

Book Chapter

Sarkar, S., Sinha, S., Saluja R., Kalra, N., (2023). Hypoxia-Induced Apoptosis in Cancer Development. In S. Mukherjee & J.R. Kanwar (Eds.), Hypoxia in Cancer: Significance and Impact on Cancer Therapy, Springer Nature.

Journal Articles

Jyothi, B., Kalra, N., & Peter, J. (2023). Isolation and characterization of Bacillus isolates and their biocontrol ability against Macrophomina phaseolina, Fusarium oxysporum, Rhizoctonia solani and Sclerotium rolfsii. Biological Control.
Kalra, N., Mukherjee, A., Sinha, S., Muralidhar, V., Serin, Y., Tiwari, A., & Verma A, K. (2022). Current updates on the association between celiac disease and cancer, and the effects of the gluten-free diet for modifying the risk. International Journal of Functional Nutrition. https://doi.org/10.3892/ijfn.2022.25
Thakur, K., Sajeev, T.K., Singh, S.K., Ragendu, V., Rawale,. D, Adusumalli , S.R., Kalra, N., Shukla, S., Mishra, R.K, & Rai, V. (2022). Human behavior-inspired linchpin-directed catalysis for traceless precision labeling of lysine in native proteins. Bioconjugate Chemistry, 33(12), 2370 – 2380. https://doi.org/10.1021/acs.bioconjchem.2c00454
Reddy, N., Molla, R., Joshi, P.N., Sajeev, T.K., Basu, I., Kawadkar, J., Kalra, N., Chakrabarty, S., Mishra, R.K., Shukla, S., & Rai, V. (2022). Traceless cysteine-linchpin enables precision engineering of lysine in native proteins. Nature Communications, 13, 6038. https://doi.org/10.1038/s41467-022 – 33772‑1
Yadav, S., Pant, D., Samaiya, A., Kalra, N., Gupta, S., & Shukla, S. (2021). ERK1/2‑EGR1-SRSF10 Axis Mediated Alternative Splicing Plays a Critical Role in Head and Neck Cancer. Frontiers in Cell and Developmental Biology. 10.3389/fcell.2021.713661
Adusumalli, S.R., Rawale, D., Thakur, K., Purushottam, L., Reddy, N., Kalra, N., Shukla, S., & Rai, V., (2020). Chemoselective and Site-Selective Lysine-Directed Lysine Modification Enables Single-Site Labeling of Native Proteins. Angewandte Chemie. https://doi.org/10.1002/anie.202000062
Adusumalli, S.R., Rawale, D., Tripathi, P.R., Paul, R., Kalra, N., Shukla, S., & Rai, V. (2018). Single-site labeling of native proteins enabled by a chemoselective and site-selective chemical technology. Journal of American Chemical Society, 140 (44), 15114 – 15123. https://doi.org/10.1021/jacs.8b10490
Chilamari, M., Kalra, N., Shukla, S., & Rai, V. (2018). Chemoselective and site-selective labeling of lysine in native proteins through phospha-Mannich reaction. Chemical Communication. https://doi.org/10.1039/C8CC03311K
Kalra, N., Zhang, J., Thomas, A., Xi, L., Cheung, M., Talarchek, J., Burkett, S., Tsokos, M.G., Chen, Y., Raffeld, M., Miettinen, M., Pastan, I., Testa, J.R., & Hassan, R. (2015). Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma. BMC Cancer. 10.1186/s12885-015‑1362‑2
Kalra, N., Ashai, A., Xi, L., Zhang, J., Avital, I., Raffeld, M., Hassan, R., (2012). Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors. Oncology Reports, 27(6), 1794 – 80. 10.3892/or.2012.1725
Kalra, N., Zhang, J., Yu, Y., Ho, M., Merino, M., Cao, L., Hassan, R., (2012). Efficacy of anti-insulin-like growth factor i receptor (IGF-IR) monoclonal antibody cixutumumab in mesothelioma is highly correlated with IGF-IR sites/cell. International Journal of Cancer. https://doi.org/10.1002%2Fijc.27471

Conference Papers

Kalra, N., Zhang, J., Yunkai, Yu., Ho, M., Cao , L., (2011, April 2 – 6). Anti-tumor Efficacy Of IMC-A12, A Fully Human Anti-insulin Like Growth Factor 1 Receptor (IGF-1R) Antibody, Against Malignant Mesothelioma, American Association of Cancer Research, 102^nd Annual Meeting. Orlando, Florida.
Singh, P.P., Singh, S., & Kalra, N., (2022, November 11 – 12). Prediction of Antimicrobial Resistance using Machine Learning. International Management Conference on Contemporary technology challenges in Business, IMCCTCB. VIT Bhopal, India.