This is the final course in the series of core courses which focuses on the chemistry of inorganic, organic and organometallic compounds. It covers patterns of reactivity, functional group chemistry, kinetics, mechanisms, and catalysis. It initiates the systematic study of the common classes of organic compounds with emphasis on theories of structure and reactivity.

Some amount of basic chemical synthesis is also introduced in the laboratory component of this course. Students are exposed to the practical aspects of working with small molecules, both organic and inorganic. Students learn to analyse and synthesize compounds and analyse their characteristic properties such as structure, function, size distribution, and purity. They use principles studied in the course to predict reactions and use these reactions to make modifications to small molecules.