Areas of Interest & Expertise
- Microbial Ecology and Taxonomy
- Antimicrobial Resistance
- Microbial life beyond Earth / Extraterrestrial microbial life
Yogesh was a research scientist at National Centre for Cell Science (NCCS), Pune, an autonomous institute under the Department of Biotechnology (DBT), Government of India, for over thirty years.
His major area of interest is microbial communities in unique ecosystems and how they interact with each other and their surroundings. In the last few years, his group has worked extensively on human microbiome of the Indian population and how it is affected by lifestyle and genetics. They have also tried to understand microbiome alteration in diseases like diabetes, obesity, Celiac disease with the aim of developing microbe-based therapeutic solutions.
At NCCS, he also developed a microbial culture collection that harbours microbes from different ecosystems, specialised microbes (cyanobacteria, anoxygenic photosynthetic bacteria, anaerobes and antibiotic-resistant microbes). This is the largest culture collection globally under one roof and is also International Depositary Authority (IDA) under the Budapest Treaty and Designated Repository under the Biological Diversity Act 2002 of India.
The other microbial ecosystems that he worked on are effluent treatment plants, impact of mass bathing event (Kumbh Mela) on the river ecosystem and stratosphere besides microbial resistance to antimicrobials and antibiotics.
He has keen interest in science popularisation and has written several articles in English as well as Marathi newspapers and magazines, besides giving talks on radio, at schools, colleges and public events.
How does life work? Answers from molecular, cellular and evolutionary perspectives.
- Mongad, D.S., Chavan, N.S., Narwade, N.P., Dixit, K., Shouche, Y.S., Dhotre, D.P. (2021). MicFunPred: A conserved approach to predict functional profiles from 16S rRNA gene sequence data. Genomics, 113(6), 3635 – 3643. https://doi.org/10.1016/j.ygeno.2021.08.016
- Gaike, A.H., Paul, D., Bhute, S., Dhotre, D.P., Pande, P., Upadhyaya, S., Reddy, Y., Sampath, R., Ghosh, D., Chandraprabha, D., Acharya, J., Banerjee, G., Sinkar, V.P., Ghaskadbi, S. S., Shouche, Y.S. (2020). The gut microbial diversity of newly diagnosed diabetics but not of prediabetics is significantly different from that of healthy nondiabetics. mSystems, 5(2). https://doi.org/10.1128/mSystems.00578 – 19
- Chaudhari, D.S., Dhotre, D.P., Agarwal, D.M, Gaike, A.H., Bhalerao, D., Jadhav, P., Mongad, D., Lubree, H., Sinkar, V.P., Patil, U.K., Salvi, S., Bavdekar, A., Juvekar, S.K., Shouche, Y.S. (2020). Gut, oral and skin microbiome of Indian patrilineal families reveal perceptible association with age. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020 – 62195‑5
- Kumbhare, S.V., Patangia, D.V., Mongad, D.S., Bora, A., Bavdekar, A.R., Shouche, Y.S. (2020). Gut microbial diversity during pregnancy and early infancy: An exploratory study in the Indian population. FEMS Microbiology Letters, 367(3). https://doi.org/10.1093/femsle/fnaa022
- Bodkhe, R., Shetty, S.A., Dhotre, D.P., Verma, A.K., Bhatia, K., Mishra, A., Kaur, G., Pande, P., Bangarusamy, D.K., Santosh, B.P., Perumal, R.C., Ahuja, V., Shouche, Y.S., Makharia, G.K. (2019). Comparison of small gut and whole gut microbiota of first-degree relatives with adult celiac disease patients and controls. Frontiers in Microbiology, 10. https://doi.org/10.3389/fmicb.2019.00164
- Kumbhare, S.V., Kumar, H., Chowdhury, S.P., Dhotre, D.P., Endo, A., Mättö, J., Ouwehand, A.C., Rautava, S., Joshi, R., Patil, N.P., Patil, R.H., Isolauri, E., Bavdekar, A.R., Salminen, S., Shouche, Y.S. (2017). A cross-sectional comparative study of gut bacterial community of Indian and Finnish children. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017 – 11215‑y
- Adebayo, A.S., Suryavanshi, M.V., Bhute, S., Agunloye, A.M., Isokpehi, R.D., Anumudu, C.I., Shouche, Y.S. (2017). The microbiome in urogenital schistosomiasis and induced bladder pathologies. PLOS Neglected Tropical Diseases. 11(8). https://doi.org/10.1371/journal.pntd.0006067
- Bhute, S.S., Suryavanshi, M.V., Joshi, S.M., Yajnik, C.S., Shouche, Y.S., Ghaskadbi, S.S. (2017). Gut microbial diversity assessment of Indian type-2-diabetics reveals alterations in Eubacteria, Archaea, and Eukaryotes. Frontiers in Microbiology, 8. https://doi.org/10.3389/fmicb.2017.00214
- Bhute, S., Pande, P., Shetty, S.A., Shelar, R., Mane, S., Kumbhare, S.V., Gawali, A., Makhani, H., Navandar, M., Dhotre, D., Lubree, H., Agarwal, D., Patil, R., Ozarkar, S., Ghaskadbi, S., Yajnik, C., Juvekar, S., Makharia, G.K., Shouche, Y.S. (2016). Molecular characterization and meta-analysis of gut microbial communities illustrate enrichment of Prevotella and Megasphaera in Indian subjects. Frontiers in Microbiology, 7. https://doi.org/10.3389/fmicb.2016.00660
- Suryavanshi, M.V., Bhute, S.S., Jadhav, S.D., Bhatia, M.S., Gune, R.P., Shouche, Y.S. (2016). Hyperoxaluria leads to dysbiosis and drives selective enrichment of oxalate metabolizing bacterial species in recurrent kidney stone endures. Scientific Reports, 6. https://doi.org/10.1038/srep34712
Click here for the complete list: https://pubmed.ncbi.nlm.nih.gov/?term=shouche+y